Sodium ion → 5-(5-chloro-2-fluorophenyl)-3-methyl-3-phenyl-2,3-dihydroisoxazole

HRID 1542218Notes

Reaction equation

HRID 1542218 reaction equation
[C:39](=[O:40])([O-:41])[O-:42].[Cl:1][c:2]1[cH:3][cH:4][c:5]([F:31])[c:6]([C:8]2=[CH:9][C:10]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)([CH3:30])[N:11]([CH2:13][c:14]3[cH:15][cH:16][c:17]([O:18][CH3:19])[cH:20][c:21]3[O:22][CH3:23])[O:12]2)[cH:7]1.[Cl:45][CH2:46][Cl:47].[Na+:43].[Na+:44].[OH:32][C:33]([C:34]([F:35])([F:36])[F:37])=[O:38]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([F:31])[c:6]([C:8]2=[CH:9][C:10]([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)([CH3:30])[NH:11][O:12]2)[cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 19660Carbonate IonHCID 57539120HCID 57539120, compound

Product 1

HCID 115438305-(5-chloro-2-fluorophenyl)-3-methyl-3-phenyl-2,3-dihydroisoxazole

Sources & evidence

ORD record
ord-367ae042dace46848fbd3fc5be588a30
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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