Dichloromethane → 4-Morpholinopiperidine

HRID 1542343Notes

Reaction equation

HRID 1542343 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:27][CH2:28][Cl:29].[OH:20][C:21]([C:22]([F:23])([F:24])[F:25])=[O:26]>>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 14571198tert-Butyl 4-(morpholin-4-yl)piperidine-1-carboxylate

Product 1

HCID 7957244-Morpholinopiperidine

Sources & evidence

ORD record
ord-ef68b893e39643debf16fe1f42c406b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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