Chloride → 2'-Cyclohexyl-5'-hydroxy-4'-methoxyacetophenone

HRID 154258Notes

Reaction equation

HRID 154258 reaction equation
[Al+3:23].[CH:1]1([c:7]2[c:8]([C:19]([CH3:20])=[O:21])[cH:9][c:10]([O:15][CH:16]([CH3:17])[CH3:18])[c:11]([O:13][CH3:14])[cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[Cl-:22].[Cl-:24].[Cl-:25].[Cl:26][CH2:27][Cl:28]>>[CH:1]1([c:7]2[c:8]([C:19]([CH3:20])=[O:21])[cH:9][c:10]([OH:15])[c:11]([O:13][CH3:14])[cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 312Chloride3×HCID 6344DichloromethaneHCID 104727Aluminum CationHCID 680368202'-Cyclohexyl-5'-isopropoxy-4'-methoxyacetophenone

Product 1

HCID 667611392'-Cyclohexyl-5'-hydroxy-4'-methoxyacetophenone

Sources & evidence

ORD record
ord-f18409a5942145eda6f37bdee791c43f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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