Dichloromethane → 1-(Methylsulfonyl)-4-[4-(2,2,2-trifluoroethoxy)phenyl]piperazine
Reaction equation
[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[CH3:26][S:27]([Cl:28])(=[O:29])=[O:30].[Cl:31][CH2:32][Cl:33].[F:1][C:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:9][cH:10]1)([F:17])[F:18]>>[F:1][C:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][N:14]([S:27]([CH3:26])(=[O:29])=[O:30])[CH2:15][CH2:16]2)[cH:9][cH:10]1)([F:17])[F:18]Participants
5
Sources & evidence
- ORD record
- ord-85d97a673c1c4c5ead66ad04fa4efc43
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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