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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1542762Generated: October 25, 2026

Tetrahydrofuran → 2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-3-hydroxy-3-(6-methoxy-[1,5]naphthyridin-4-yl)-propionic acid ethyl ester

https://huagongshe.com/reaction/1542762

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
ReactantEthyl 2-(1,4-dioxaspiro[4.5]decan-8-yl)acetateHCID 15700391—
Reactant1,5-Naphthyridine-4-carboxaldehyde, 6-methoxy-HCID 66523138—
Product2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-3-hydroxy-3-(6-methoxy-[1,5]naphthyridin-4-yl)-propionic acid ethyl esterHCID 67445919—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-8219c71a737340d09e17de331f9ec83d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)