Tetrahydrofuran → 2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-3-hydroxy-3-(6-methoxy-[1,5]naphthyridin-4-yl)-propionic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH:6]1[CH2:7][CH2:8][C:9]2([O:10][CH2:11][CH2:12][O:13]2)[CH2:14][CH2:15]1)=[O:16].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:18][Si:19]([N-:20][Si:21]([CH3:22])([CH3:23])[CH3:24])([CH3:25])[CH3:26].[CH3:27][O:28][c:29]1[n:30][c:31]2[c:32]([CH:39]=[O:40])[cH:33][cH:34][n:35][c:36]2[cH:37][cH:38]1.[Li+:17]>>[CH2:1]([CH3:2])[O:3][C:4]([CH:5]([CH:6]1[CH2:7][CH2:8][C:9]2([O:10][CH2:11][CH2:12][O:13]2)[CH2:14][CH2:15]1)[CH:39]([c:32]1[c:31]2[n:30][c:29]([O:28][CH3:27])[cH:38][cH:37][c:36]2[n:35][cH:34][cH:33]1)[OH:40])=[O:16]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8219c71a737340d09e17de331f9ec83d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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