Triethylamine → 2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1-[4-(5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)piperidin-1-yl]-4-[4-(2-oxo-4,5-dihydro-1H-1,3-benzodiazepin-3-yl)piperidin-1-yl]butane-1,4-dione
Reaction equation
[CH3:39][N:40]1[CH:41]2[CH2:42][N:43]([CH:47]3[CH2:48][CH2:49][NH:50][CH2:51][CH2:52]3)[CH:44]([CH2:45]1)[CH2:46]2.[CH3:53][CH2:54][N:55]([CH2:56][CH3:57])[CH2:58][CH3:59].[NH2:1][c:2]1[c:3]([Cl:38])[cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[CH2:11][C:12]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:30])[NH:21][c:22]4[c:23]([cH:26][cH:27][cH:28][cH:29]4)[CH2:24][CH2:25]3)[CH2:17][CH2:18]2)=[O:31])[cH:32][c:33]1[C:34]([F:35])([F:36])[F:37]>>[NH2:1][c:2]1[c:3]([Cl:38])[cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:10])[N:50]2[CH2:49][CH2:48][CH:47]([N:43]3[CH2:42][CH:41]4[N:40]([CH3:39])[CH2:45][CH:44]3[CH2:46]4)[CH2:52][CH2:51]2)[CH2:11][C:12]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:30])[NH:21][c:22]4[c:23]([cH:26][cH:27][cH:28][cH:29]4)[CH2:24][CH2:25]3)[CH2:17][CH2:18]2)=[O:31])[cH:32][c:33]1[C:34]([F:35])([F:36])[F:37]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-3c57bac2b7454ec68e5244a45845c96a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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