Acetic Acid → Ethyl 4-(4-chloro-2-nitrophenyl)-4-hydroxy-2-butynoate
Reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:1][CH2:2][O:3][C:4](=[O:5])[C:6]#[CH:7].[CH3:25][C:26](=[O:27])[OH:28].[CH3:34][CH2:35][O:36][CH2:37][CH3:38].[Cl:13][c:14]1[cH:15][c:16]([N+:22](=[O:23])[O-:24])[c:17]([CH:18]=[O:19])[cH:20][cH:21]1>>[CH3:1][CH2:2][O:3][C:4](=[O:5])[C:6]#[C:7][CH:18]([c:17]1[c:16]([N+:22](=[O:23])[O-:24])[cH:15][c:14]([Cl:13])[cH:21][cH:20]1)[OH:19]Participants
7
Sources & evidence
- ORD record
- ord-446f23b7a7ca47a7b06252ee9749b406
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…