Acetic Acid → 2-[1-(Piperidin-3-yl)-ethylamino]-4-[benzimidazol-1-yl]pyrimidine

HRID 1543650Notes

Reaction equation

HRID 1543650 reaction equation
[BrH:35].[CH2:1]([O:2][C:3](=[O:4])[N:11]1[CH2:12][CH:13]([CH:17]([CH3:18])[NH:19][c:20]2[n:21][cH:22][cH:23][c:24](-[n:26]3[cH:27][n:28][c:29]4[c:30]3[cH:31][cH:32][cH:33][cH:34]4)[n:25]2)[CH2:14][CH2:15][CH2:16]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH3:39][C:40](=[O:41])[OH:42].[Cl:36][CH2:37][Cl:38]>>[NH:11]1[CH2:12][CH:13]([CH:17]([CH3:18])[NH:19][c:20]2[n:21][cH:22][cH:23][c:24](-[n:26]3[cH:27][n:28][c:29]4[c:30]3[cH:31][cH:32][cH:33][cH:34]4)[n:25]2)[CH2:14][CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 6344DichloromethaneHCID 155505842-[1-(1-Benzyloxycarbonylpiperidin-3-yl)-ethylamino]-4-[benzimidazol-1-yl]pyrimidine

Product 1

HCID 183326302-[1-(Piperidin-3-yl)-ethylamino]-4-[benzimidazol-1-yl]pyrimidine

Sources & evidence

ORD record
ord-6fb30aec162d4edbaa4d35ba37c7c8f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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