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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 154367Generated: October 28, 2026

Ammonium → 8-[2-(4-Fluoro-phenyl)-2-hydroxy-cyclohexyl]-4-phenyl-2,8-diaza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/154367

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Bromo-4-fluorobenzeneHCID 9993—
Reactant8-(2-Oxo-cyclohexyl)-4-phenyl-2,8-diaza-spiro[4.5]decan-1-oneHCID 21082565—
ReactantButyllithiumHCID 178418339—
Product8-[2-(4-Fluoro-phenyl)-2-hydroxy-cyclohexyl]-4-phenyl-2,8-diaza-spiro[4.5]decan-1-oneHCID 11212373—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-82e2e9a5d972406b8a230f483d46e5be
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)