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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1543767Generated: October 30, 2026

Tetrahydrofuran → 3-Cyclopentyl-2-(4-fluoro-3-trifluoromethyl-phenyl)-propionic acid

https://huagongshe.com/reaction/1543767

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-HCID 81646—
Reactant4-Fluoro-3-(trifluoromethyl)phenylacetic acidHCID 2737593—
Reactant(Iodomethyl)cyclopentaneHCID 2762531—
ReactantDiisopropylamideHCID 5062348—
Product3-Cyclopentyl-2-(4-fluoro-3-trifluoromethyl-phenyl)-propionic acidHCID 12069500—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-c79609b2ecd34860b4e5594d2c6baaf7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)