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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1543883Generated: October 30, 2026

Acetonitrile → 5-(4-Hydroxy-but-1-ynyl)-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1543883

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
Reactant3-Butyn-1-OLHCID 13566—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper iodideHCID 83717—
ReactantMethyl 5-bromothiophene-2-carboxylateHCID 605713—
Product5-(4-Hydroxy-but-1-ynyl)-thiophene-2-carboxylic acid methyl esterHCID 15735939—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-afc262f1dddd4c3a8f65a78b3dac103b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)