Methane → 2-({(3,5-Bis-trifluoromethyl-benzyl)-[5-(2-methanesulfonyl-ethoxy)-pyrimidin-2-yl]-amino}-methyl)-4-trifluoromethyl-phenol
Reaction equation
[C:52].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([CH2:11][N:12]([c:13]2[n:14][cH:15][c:16]([O:19][CH2:20][CH2:21][S:22](=[O:23])(=[O:24])[CH3:25])[cH:17][n:18]2)[CH2:26][c:27]2[cH:28][c:29]([C:37]([F:38])([F:39])[F:40])[cH:30][c:31]([C:33]([F:34])([F:35])[F:36])[cH:32]2)[cH:41][c:42]([C:45]([F:46])([F:47])[F:48])[cH:43][cH:44]1.[CH3:49][CH2:50][OH:51].[Pd:53]>>[OH:8][c:9]1[c:10]([CH2:11][N:12]([c:13]2[n:14][cH:15][c:16]([O:19][CH2:20][CH2:21][S:22](=[O:23])(=[O:24])[CH3:25])[cH:17][n:18]2)[CH2:26][c:27]2[cH:28][c:29]([C:37]([F:38])([F:39])[F:40])[cH:30][c:31]([C:33]([F:34])([F:35])[F:36])[cH:32]2)[cH:41][c:42]([C:45]([F:46])([F:47])[F:48])[cH:43][cH:44]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-c03f738e562c43269fe8c6eb6e0c6849
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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