Sodium ion → tert-Butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[3-(3-methoxypropyl)-2-oxo-2,3-dihydrobenzoxazol-5-ylmethoxy]piperidine-1-carboxylate

HRID 1544350Notes

Reaction equation

HRID 1544350 reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:5][O:6][CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14]([CH:17]3[CH:18]([O:30][CH2:31][c:32]4[cH:33][cH:34][c:35]5[c:36]([nH:37][c:38](=[O:40])[o:39]5)[cH:41]4)[CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]3)[cH:15][cH:16]2)[cH:42][cH:43][cH:44][cH:45]1.[CH3:56][N:57]([CH3:58])[CH:59]=[O:60].[Cl:48][CH2:49][CH2:50][CH2:51][O:52][CH3:53].[H-:46].[I-:55].[Na+:47].[Na+:54]>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][O:6][CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14]([CH:17]3[CH:18]([O:30][CH2:31][c:32]4[cH:33][cH:34][c:35]5[c:36]([n:37]([CH2:49][CH2:50][CH2:51][O:52][CH3:53])[c:38](=[O:40])[o:39]5)[cH:41]4)[CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]3)[cH:15][cH:16]2)[cH:42][cH:43][cH:44][cH:45]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 30165Iodide IonHCID 1189271-Chloro-3-methoxypropaneHCID 166653HydrideHCID 178489539HCID 178489539, compound

Product 1

HCID 68503770tert-Butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[3-(3-methoxypropyl)-2-oxo-2,3-dihydrobenzoxazol-5-ylmethoxy]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-84262eece15d4ad7a87d4444dc436c13
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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