Bicarbonate Ion → N-(1-(2-(7-Methoxyquinolin-4-yloxy)ethyl)-6-oxo-1,6-dihydropyridin-3-yl)benzamide

HRID 1544477Notes

Reaction equation

HRID 1544477 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](=[O:23])[n:6]([CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:21][CH3:22])[cH:18][cH:19][c:20]23)[cH:7]1.[C:33](=[O:34])([O-:35])[O-:36].[CH3:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[Cl:53][CH2:54][Cl:55].[Cs+:37].[Cs+:38].[Cu:51][I:52].[NH2:24][C:25](=[O:26])[c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1.[Na+:43].[O-:39][C:40]([OH:41])=[O:42]>>[c:2]1([NH:24][C:25](=[O:26])[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:3][cH:4][c:5](=[O:23])[n:6]([CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:21][CH3:22])[cH:18][cH:19][c:20]23)[cH:7]1

Participants

10

Reactant 9

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 1140TolueneHCID 2331BenzamideHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 104967Cesium cation2×HCID 248844955-Bromo-1-(2-(7-methoxyquinolin-4-yloxy)ethyl)pyridin-2(1H)-one

Product 1

HCID 25019423N-(1-(2-(7-Methoxyquinolin-4-yloxy)ethyl)-6-oxo-1,6-dihydropyridin-3-yl)benzamide

Sources & evidence

ORD record
ord-f84929b8ac15477c804313217310c0c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…