Dimethyl Sulfoxide → 3-[(3,4-Dichlorophenyl)-(4-fluorophenyl)amino]pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[O:27][C:28](=[O:29])[N:30]1[CH2:31][CH:32]([O:35][S:36]([c:37]2[cH:38][cH:39][c:40]([CH3:41])[cH:42][cH:43]2)(=[O:44])=[O:45])[CH2:33][CH2:34]1.[CH3:3][S:4](=[O:5])[CH3:6].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[Cl:7][c:8]1[cH:9][c:10]([NH:15][c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[cH:11][cH:12][c:13]1[Cl:14].[H-:1].[Na+:2]>>[Cl:7][c:8]1[cH:9][c:10]([N:15]([c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[CH:32]2[CH2:31][N:30]([C:28]([O:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:29])[CH2:34][CH2:33]2)[cH:11][cH:12][c:13]1[Cl:14]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-57b1cf853675439b84d12a3b4d8657a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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