Toluene → 4-(4-Chloromethylphenoxymethyl)-5-methyl-2-phenylthiazole

HRID 1544802Notes

Reaction equation

HRID 1544802 reaction equation
[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[CH3:5][c:6]1[c:7]([CH2:17][O:18][c:19]2[cH:20][cH:21][c:22]([CH2:23][OH:24])[cH:25][cH:26]2)[n:8][c:9](-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[s:10]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1.[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:3][CH2:23][c:22]1[cH:21][cH:20][c:19]([O:18][CH2:17][c:7]2[c:6]([CH3:5])[s:10][c:9](-[c:11]3[cH:12][cH:13][cH:14][cH:15][cH:16]3)[n:8]2)[cH:26][cH:25]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 8028TetrahydrofuranHCID 24386Thionyl ChlorideHCID 688862694-(5-Methyl-2-phenyl-4-thiazolylmethoxy)benzyl alcohol

Product 1

HCID 178613534-(4-Chloromethylphenoxymethyl)-5-methyl-2-phenylthiazole

Sources & evidence

ORD record
ord-3a2b8adad6ab45b9a6b4fa0194bc2bd1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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