Pyridine → HCID 178473462, compound

HRID 1545613Notes

Reaction equation

[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[Cl:37][C:38](=[O:39])[O:40][CH2:41][CH3:42].[NH2:1][c:2]1[n:3][n:4]2[c:5]([n:31]1)[N:6]([c:21]1[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]1)[C:7]([CH3:20])=[C:8]([C:18]#[N:19])[CH:9]2[c:10]1[cH:11][cH:12][c:13]([C:16]#[N:17])[cH:14][cH:15]1.[cH:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1>>[NH:1]([c:2]1[n:3][n:4]2[c:5]([n:31]1)[N:6]([c:21]1[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]1)[C:7]([CH3:20])=[C:8]([C:18]#[N:19])[CH:9]2[c:10]1[cH:11][cH:12][c:13]([C:16]#[N:17])[cH:14][cH:15]1)[C:38](=[O:39])[O:40][CH2:41][CH3:42]

Participants

Reactant 4

HCID 1049Pyridine

HCID 8028Tetrahydrofuran

HCID 10928Ethyl chloroformate

HCID 712318442-amino-7-(4-cyanophenyl)-5-methyl-4-[3-(trifluoromethyl)phenyl]-7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile

Product 1

HCID 178473462HCID 178473462, compound

Sources & evidence

ORD record: ord-aa330f91a3bb4848adb29ad59fe8181c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…