Potassium Cation → [12-[(2,4-Difluorophenyl)methylcarbamoyl]-6-methyl-8,11-dioxo-4-oxa-1,7-diazatricyclo[7.4.0.03,7]trideca-9,12-dien-10-yl]oxymethyl 2-(2-methoxyethoxy)ethyl carbonate

HRID 1545634Notes

Reaction equation

HRID 1545634 reaction equation
[C:1]([O:2][CH2:3][I:4])([O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11][CH3:12])=[O:13].[C:44](=[O:45])([O-:46])[O-:47].[CH2:55]([N+:56]([CH2:57][CH2:58][CH2:59][CH3:60])([CH2:61][CH2:62][CH2:63][CH3:64])[CH2:65][CH2:66][CH2:67][CH3:68])[CH2:69][CH2:70][CH3:71].[F:15][c:16]1[c:17]([CH2:23][NH:24][C:25](=[O:26])[c:27]2[c:28](=[O:43])[c:29]([OH:42])[c:30]3[n:31]([cH:41]2)[CH2:32][CH:33]2[N:34]([C:35]3=[O:36])[CH:37]([CH3:40])[CH2:38][O:39]2)[cH:18][cH:19][c:20]([F:22])[cH:21]1.[K+:48].[K+:49].[Na:14].[S:50]([O-:51])([OH:52])(=[O:53])=[O:54]>>[C:1]([O:2][CH2:3][O:42][c:29]1[c:28](=[O:43])[c:27]([C:25]([NH:24][CH2:23][c:17]2[c:16]([F:15])[cH:21][c:20]([F:22])[cH:19][cH:18]2)=[O:26])[cH:41][n:31]2[c:30]1[C:35](=[O:36])[N:34]1[CH:33]([CH2:32]2)[O:39][CH2:38][CH:37]1[CH3:40])([O:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][O:11][CH3:12])=[O:13]

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 61778Sulfate, hydrogenHCID 5360545SodiumHCID 66799609Oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide, N-[(2,4-difluorophenyl)methyl]-2,3,5,7,11,11a-hexahydro-6-hydroxy-3-methyl-5,7-dioxo-, (3S,11aR)-;Oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide, N-[(2,4-difluorophenyl)methyl]-2,3,5,7,11,11a-hexahydro-6-hydroxy-3-methyl-5,7-dioxo-, (3S,11aR)-HCID 86055900Iodomethyl 2-{[2-(methyloxy)ethyl]oxy}ethyl carbonate

Product 1

HCID 75057909[12-[(2,4-Difluorophenyl)methylcarbamoyl]-6-methyl-8,11-dioxo-4-oxa-1,7-diazatricyclo[7.4.0.03,7]trideca-9,12-dien-10-yl]oxymethyl 2-(2-methoxyethoxy)ethyl carbonate

Sources & evidence

ORD record
ord-75e6bf76238b4b9bbc8f3a85aecd2ed7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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