Dichloromethane → Ethyl 3-(4-chlorophenyl)-2-methyl-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propanoate

HRID 1545722Notes

Reaction equation

HRID 1545722 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH3:15])[c:16]2[cH:17][n:18]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[c:19]3[c:20]([CH2:25][S:26][CH3:27])[cH:21][cH:22][cH:23][c:24]23)[cH:6][cH:7]1.[Cl:42][CH2:43][Cl:44].[OH:35][C:36]([C:37]([F:38])([F:39])[F:40])=[O:41]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH3:15])[c:16]2[cH:17][nH:18][c:19]3[c:20]([CH2:25][S:26][CH3:27])[cH:21][cH:22][cH:23][c:24]23)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 58392107tert-Butyl 3-[1-(4-chlorophenyl)-3-ethoxy-2-methyl-3-oxopropyl]-7-[(methylsulfanyl)methyl]-1H-indole-1-carboxylate

Product 1

HCID 58392240Ethyl 3-(4-chlorophenyl)-2-methyl-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propanoate

Sources & evidence

ORD record
ord-191c6f286b7a4786ad23ea3fe636cfd2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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