Dichloromethane → 2-Hydroxy-1-[3-[[2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]azetidin-1-yl]-2-methylpropan-1-one
Reaction equation
[CH3:51][CH2:52][N:53]=[C:54]=[N:55][CH2:56][CH2:57][CH2:58][N:59]([CH3:60])[CH3:61].[Cl:62][CH2:63][Cl:64].[NH:1]1[CH2:2][CH:3]([CH2:5][c:6]2[n:7]([CH3:33])[c:8]3[n:9][c:10](-[n:21]4[c:22]([CH:30]([CH3:31])[OH:32])[n:23][c:24]5[c:25]4[cH:26][cH:27][cH:28][cH:29]5)[n:11][c:12]([N:15]4[CH2:16][CH2:17][O:18][CH2:19][CH2:20]4)[c:13]3[n:14]2)[CH2:4]1.[OH:34][C:35]([C:36](=[O:37])[OH:38])([CH3:39])[CH3:40].[OH:41][n:42]1[c:43]2[c:44]([cH:45][cH:46][cH:47][cH:48]2)[n:49][n:50]1>>[N:1]1([C:36]([C:35]([OH:34])([CH3:39])[CH3:40])=[O:37])[CH2:2][CH:3]([CH2:5][c:6]2[n:7]([CH3:33])[c:8]3[n:9][c:10](-[n:21]4[c:22]([CH:30]([CH3:31])[OH:32])[n:23][c:24]5[c:25]4[cH:26][cH:27][cH:28][cH:29]5)[n:11][c:12]([N:15]4[CH2:16][CH2:17][O:18][CH2:19][CH2:20]4)[c:13]3[n:14]2)[CH2:4]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2f6935df1ab24a8c9f5f6d555374f145
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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