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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1545778Generated: October 25, 2026

Tetrahydrofuran → trans-2-(4-Tert-butoxycarbonylamino-cyclohexyl)-3-hydroxy-3-(6-methoxy-[1,5]naphthyridin-4-yl)-propionic acid methyl ester

https://huagongshe.com/reaction/1545778

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantNpc316347HCID 3280088—
Reactant4-N-BOC-cyclohexyacetic acid methyl esterHCID 26192827—
Reactant1,5-Naphthyridine-4-carboxaldehyde, 6-methoxy-HCID 66523138—
Producttrans-2-(4-Tert-butoxycarbonylamino-cyclohexyl)-3-hydroxy-3-(6-methoxy-[1,5]naphthyridin-4-yl)-propionic acid methyl esterHCID 67444344—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-2df851dc431a40bebac6eb3d6b691417
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)