Tetrahydrofuran → trans-2-(4-Tert-butoxycarbonylamino-cyclohexyl)-3-hydroxy-3-(6-methoxy-[1,5]naphthyridin-4-yl)-propionic acid methyl ester
Reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:1][O:2][C:3]([CH2:4][CH:5]1[CH2:6][CH2:7][CH:8]([NH:11][C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10]1)=[O:19].[CH3:21][Si:22]([N-:23][Si:24]([CH3:25])([CH3:26])[CH3:27])([CH3:28])[CH3:29].[CH3:30][O:31][c:32]1[n:33][c:34]2[c:35]([CH:42]=[O:43])[cH:36][cH:37][n:38][c:39]2[cH:40][cH:41]1.[Li+:20]>>[CH3:1][O:2][C:3]([CH:4]([CH:5]1[CH2:6][CH2:7][CH:8]([NH:11][C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:9][CH2:10]1)[CH:42]([c:35]1[c:34]2[n:33][c:32]([O:31][CH3:30])[cH:41][cH:40][c:39]2[n:38][cH:37][cH:36]1)[OH:43])=[O:19]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2df851dc431a40bebac6eb3d6b691417
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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