Tetrahydrofuran → Tert-butyl 2-[4-(2-hydroxyethyl)phenyl]-2,8-diazaspiro[4.5]decane-8-carboxylate
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH2:8][c:9]1[cH:10][cH:11][c:12]([N:15]2[CH2:16][C:17]3([CH2:18][CH2:19]2)[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]3)[cH:13][cH:14]1)([CH3:5])([CH3:32])[CH3:33].[CH3:35][CH2:36][CH2:37][CH2:38][N+:39]([CH2:40][CH2:41][CH2:42][CH3:43])([CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH2:50][CH3:51].[F-:34].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[OH:6][CH2:7][CH2:8][c:9]1[cH:10][cH:11][c:12]([N:15]2[CH2:16][C:17]3([CH2:18][CH2:19]2)[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]3)[cH:13][cH:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-32c694ee8d5643048a4ed31d247ffc5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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