Hydrochloric Acid → N-(2-azabicyclo[3.1.0]hexan-3-ylmethyl)-5-bromopyrimidin-2-amine

HRID 1546110Notes

Reaction equation

HRID 1546110 reaction equation
[C:2]([O:3][C:4](=[O:5])[N:9]1[CH:10]2[CH2:11][CH:12]2[CH2:13][CH:14]1[CH2:15][NH:16][c:17]1[n:18][cH:19][c:20]([Br:23])[cH:21][n:22]1)([CH3:6])([CH3:7])[CH3:8].[ClH:1].[O:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1>>[NH:9]1[CH:10]2[CH2:11][CH:12]2[CH2:13][CH:14]1[CH2:15][NH:16][c:17]1[n:18][cH:19][c:20]([Br:23])[cH:21][n:22]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 178452259tert-butyl 3-[[(5-bromopyrimidin-2-yl)amino]methyl]-2-azabicyclo[3.1.0]hexane-2-carboxylate

Product 1

HCID 67081464N-(2-azabicyclo[3.1.0]hexan-3-ylmethyl)-5-bromopyrimidin-2-amine

Sources & evidence

ORD record
ord-b1293f729f4b4b26837264f03ecf5c3b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…