Acetate → N-(cyclopropylmethyl)-5-(3-formyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl)nicotinamide
Reaction equation
[Br:32][c:33]1[cH:34][n:35][cH:36][c:37]([C:38](=[O:39])[NH:40][CH2:41][CH:42]2[CH2:43][CH2:44]2)[cH:45]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([CH:17]=[O:18])[n:6][n:7]([CH:11]3[O:12][CH2:13][CH2:14][CH2:15][CH2:16]3)[c:8]2[cH:9][cH:10]1.[K+:23].[K+:29].[K+:30].[K+:31].[O-:19][C:20]([CH3:21])=[O:22].[O:124]=[CH:125][N:126]([CH3:127])[CH3:128].[OH2:123].[P:24]([O-:25])([O-:26])([O-:27])=[O:28].[cH:46]1[cH:47][cH:48][c:49]([P:50]([Pd:51]([P:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[P:90]([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)([c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[cH:121][cH:122]1>>[c:2]1(-[c:33]2[cH:34][n:35][cH:36][c:37]([C:38](=[O:39])[NH:40][CH2:41][CH:42]3[CH2:43][CH2:44]3)[cH:45]2)[cH:3][c:4]2[c:5]([CH:17]=[O:18])[n:6][n:7]([CH:11]3[O:12][CH2:13][CH2:14][CH2:15][CH2:16]3)[c:8]2[cH:9][cH:10]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-94c02f75869740739e5dfd0cf82aa760
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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