Borohydride → 5-(3-Chlorophenyl)-6-(5-chloro-2-pyridinyl)-1-(1-hydroxybutan-2-yl)piperidin-2-one
Reaction equation
[BH4-:30].[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH:9]([c:23]3[n:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]3)[N:10]([CH:15]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[CH2:21][CH3:22])[C:11](=[O:14])[CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1.[Li+:31]>>[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH:9]([c:23]3[n:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]3)[N:10]([CH:15]([CH2:16][OH:17])[CH2:21][CH3:22])[C:11](=[O:14])[CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-7cc59e2c4ab74926b29e2eafb2291810
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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