Methanol → 2-(4-fluorophenyl)-N-methyl-6-(3-(2-phenylpropan-2-ylcarbamoyl)phenyl)imidazo-[1,2-a]pyridine-3-carboxamide

HRID 1546994Notes

Reaction equation

HRID 1546994 reaction equation
[CH3:69][OH:70].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][c:13](-[c:16]4[cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23][cH:24]4)[cH:14][cH:15]3)[c:25]2[C:26]([NH:27][CH3:28])=[O:29])[cH:6][cH:7]1.[O:40]=[CH:41][N:42]([CH3:43])[CH3:44].[P-:45]([F:46])([F:47])([F:48])([F:49])([F:50])[F:51].[c:30]1([C:36]([CH3:37])([CH3:38])[NH2:39])[cH:31][cH:32][cH:33][cH:34][cH:35]1.[n:52]1([O:53][C:54]([N:55]([CH3:56])[CH3:57])=[N+:58]([CH3:59])[CH3:60])[c:61]2[n:62][cH:63][cH:64][cH:65][c:66]2[n:67][n:68]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][c:13](-[c:16]4[cH:17][c:18]([C:19](=[O:21])[NH:39][C:36]([c:30]5[cH:31][cH:32][cH:33][cH:34][cH:35]5)([CH3:37])[CH3:38])[cH:22][cH:23][cH:24]4)[cH:14][cH:15]3)[c:25]2[C:26]([NH:27][CH3:28])=[O:29])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 887MethanolHCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 68509CumylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 592336813-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)imidazo[1,2-a]pyridin-6-yl)benzoic acid

Product 1

HCID 592337302-(4-fluorophenyl)-N-methyl-6-(3-(2-phenylpropan-2-ylcarbamoyl)phenyl)imidazo-[1,2-a]pyridine-3-carboxamide

Sources & evidence

ORD record
ord-354eba1706294a5f899f180cf21bb971
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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