Dichloromethane → 5-(4-bromo-naphthalen-1-yl)-2-pyrrolidin-2-yl-1H-imidazole

HRID 1547073Notes

Reaction equation

HRID 1547073 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([c:13]2[nH:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([Br:28])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]34)[cH:16][n:17]2)[CH2:10][CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[NH:8]1[CH:9]([c:13]2[nH:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([Br:28])[c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]34)[cH:16][n:17]2)[CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 666204542-[5-(4-Bromo-naphthalen-1-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 666201165-(4-bromo-naphthalen-1-yl)-2-pyrrolidin-2-yl-1H-imidazole

Sources & evidence

ORD record
ord-39e4cb35f4844929933a0d5c174fdebb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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