Sodium ion → Tert-butyl 4-{2-[(3,5-dichloro-benzyl)-(5'-isopropyl-2'-methoxy-4-trifluoromethyl-biphenyl-2-ylmethyl)-amino]-pyrimidin-5-yloxy}-butyrate
Reaction equation
[CH3:53][N:54]([CH3:55])[CH:56]=[O:57].[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([O:39][CH3:40])[c:8](-[c:10]2[c:11]([CH2:20][NH:21][c:22]3[n:23][cH:24][c:25]([O:28][CH2:29][CH2:30][CH2:31][C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[cH:26][n:27]3)[cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[cH:9]1.[Cl:41][c:42]1[cH:43][c:44]([Cl:50])[cH:45][c:46]([CH2:48][Cl:49])[cH:47]1.[H-:51].[Na+:52]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([O:39][CH3:40])[c:8](-[c:10]2[c:11]([CH2:20][N:21]([c:22]3[n:23][cH:24][c:25]([O:28][CH2:29][CH2:30][CH2:31][C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[cH:26][n:27]3)[CH2:48][c:46]3[cH:45][c:44]([Cl:50])[cH:43][c:42]([Cl:41])[cH:47]3)[cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[cH:9]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c7c323e10ac34edfa13ae590454d26d4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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