Sodium ion → 3-(2,6-Difluoro-4-pyridinyl)-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine

HRID 1547866Notes

Reaction equation

HRID 1547866 reaction equation
[Br:1][c:2]1[c:3](-[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[n:4][n:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2.[F:18][c:19]1[n:20][c:21]([F:28])[cH:22][c:23]([B:25]([OH:26])[OH:27])[cH:24]1.[Na+:29].[Na+:30].[O-:31][C:32](=[O:33])[O-:34].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[c:2]1(-[c:23]2[cH:22][c:21]([F:28])[n:20][c:19]([F:18])[cH:24]2)[c:3](-[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[n:4][n:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 27627472,6-Difluoropyridine-4-boronic acidHCID 219486782-(4-Fluorophenyl)-3-bromopyrazolo[1,5-a]pyridine

Product 1

HCID 98584533-(2,6-Difluoro-4-pyridinyl)-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridine

Sources & evidence

ORD record
ord-7f55e901a8094497aa6456b87c5a8331
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…