Methane → tert-butyl N-methyl-N-(1-pyrrolidin-3-ylcyclopropyl)carbamate

HRID 1548560Notes

Reaction equation

HRID 1548560 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[C:10]1([CH:13]2[CH2:14][N:15]([CH:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH3:25])[CH2:16][CH2:17]2)[CH2:11][CH2:12]1.[C:29].[CH3:26][CH2:27][OH:28].[Pd:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH3:9])[C:10]1([CH:13]2[CH2:14][NH:15][CH2:16][CH2:17]2)[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 297MethaneHCID 702EthanolHCID 23938PalladiumHCID 67271081tert-butyl N-methyl-N-[1-[1-(1-phenylethyl)pyrrolidin-3-yl]cyclopropyl]carbamate

Product 1

HCID 67271847tert-butyl N-methyl-N-(1-pyrrolidin-3-ylcyclopropyl)carbamate

Sources & evidence

ORD record
ord-1bb5ba71d15745d997ceb9875a2d97ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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