Hydrochloric Acid → N-(4-(6-(2-Amino-4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamide

HRID 1548578Notes

Reaction equation

HRID 1548578 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9](-[c:18]2[n:19][cH:20][n:21][c:22]([O:24][c:25]3[cH:26][cH:27][cH:28][c:29]4[c:30]3[n:31][c:32]([NH:34][C:35]([CH3:36])=[O:37])[s:33]4)[cH:23]2)[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1)([CH3:5])([CH3:6])[CH3:38].[ClH:39].[O:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1>>[NH2:7][c:8]1[c:9](-[c:18]2[n:19][cH:20][n:21][c:22]([O:24][c:25]3[cH:26][cH:27][cH:28][c:29]4[c:30]3[n:31][c:32]([NH:34][C:35]([CH3:36])=[O:37])[s:33]4)[cH:23]2)[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 11957782tert-Butyl-2-(6-((2-(acetylamino)-1,3-benzothiazol-4-yl)oxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenylcarbamate

Product 1

HCID 21865046N-(4-(6-(2-Amino-4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamide

Sources & evidence

ORD record
ord-23ea21fff36a47fa9365b45a79245f28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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