Acetonitrile → 2-(5-(3-Amino-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-1-yl)-2-methoxy-3-methylphenyl) acetonitrile
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][c:5]([C:12]2([c:23]3[cH:24][c:25](-[c:29]4[cH:30][n:31][cH:32][n:33][cH:34]4)[cH:26][cH:27][cH:28]3)[N:13]=[C:14]([NH2:22])[c:15]3[c:16]([F:21])[cH:17][cH:18][cH:19][c:20]32)[cH:6][c:7]([CH3:11])[c:8]1[O:9][CH3:10].[CH3:38][C:39]#[N:40].[K:35][C:36]#[N:37]>>[CH2:2]([c:3]1[cH:4][c:5]([C:12]2([c:23]3[cH:24][c:25](-[c:29]4[cH:30][n:31][cH:32][n:33][cH:34]4)[cH:26][cH:27][cH:28]3)[N:13]=[C:14]([NH2:22])[c:15]3[c:16]([F:21])[cH:17][cH:18][cH:19][c:20]32)[cH:6][c:7]([CH3:11])[c:8]1[O:9][CH3:10])[C:36]#[N:37]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-38ad3b8feb594d05ada96135f57c7733
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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