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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1548633Generated: October 31, 2026

Acetonitrile → 2-(5-(3-Amino-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-1-yl)-2-methoxy-3-methylphenyl) acetonitrile

https://huagongshe.com/reaction/1548633

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant1-(3-(Bromomethyl)-4-methoxy-5-methylphenyl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amineHCID 58579476—
ReactantHCID 178511842HCID 178511842—
Product2-(5-(3-Amino-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-1-yl)-2-methoxy-3-methylphenyl) acetonitrileHCID 58579489—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-38ad3b8feb594d05ada96135f57c7733
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)