Dichloromethane → 6-Chloro-4-(o-tolyl)nicotinonitrile

HRID 1548805Notes

Reaction equation

HRID 1548805 reaction equation
[Cl:22][CH2:23][Cl:24].[OH:1][c:2]1[n:3][cH:4][c:5]([C:6]#[N:7])[c:8](-[c:10]2[c:11]([CH3:16])[cH:12][cH:13][cH:14][cH:15]2)[cH:9]1.[P:17]([Cl:18])([Cl:19])([Cl:20])=[O:21]>>[c:2]1([Cl:19])[n:3][cH:4][c:5]([C:6]#[N:7])[c:8](-[c:10]2[c:11]([CH3:16])[cH:12][cH:13][cH:14][cH:15]2)[cH:9]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24813Phosphorus oxychlorideHCID 178424179HCID 178424179, compound

Product 1

HCID 113681836-Chloro-4-(o-tolyl)nicotinonitrile

Sources & evidence

ORD record
ord-87efc3592a22465ca412ba007e1857ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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