Bromide ion → 1-(4-Amino-3'-chloro-biphenyl-3-yl)-1-cyclopropyl-ethanol

HRID 1548890Notes

Reaction equation

HRID 1548890 reaction equation
[Br-:20].[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:21][Mg+:22].[NH2:1][c:2]1[c:3]([C:15](=[O:16])[CH:17]2[CH2:18][CH2:19]2)[cH:4][c:5](-[c:8]2[cH:9][c:10]([Cl:14])[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1>>[NH2:1][c:2]1[c:3]([C:15]([OH:16])([CH:17]2[CH2:18][CH2:19]2)[CH3:21])[cH:4][c:5](-[c:8]2[cH:9][c:10]([Cl:14])[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 23509605(4-Amino-3'-chloro-biphenyl-3-yl)-cyclopropyl-methanoneHCID 178477777HCID 178477777, compound

Product 1

HCID 235096211-(4-Amino-3'-chloro-biphenyl-3-yl)-1-cyclopropyl-ethanol

Sources & evidence

ORD record
ord-e4fcecc38a224afbbebd0059c02c4551
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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