Tetrahydrofuran → Tert-butyl 4-[2-(4-fluorophenyl)-3-iodoimidazo[1,2-b]pyridazin-6-yl]piperazine-1-carboxylate
Reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([n:12][c:13]([N:16]4[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]4)[cH:14][cH:15]3)[cH:29]2)[cH:6][cH:7]1.[I:30][N:31]1[C:32](=[O:33])[CH2:34][CH2:35][C:36]1=[O:37].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([n:12][c:13]([N:16]4[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]4)[cH:14][cH:15]3)[c:29]2[I:30])[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-ba2ed61286024b0abbbbc6bc5110f7c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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