Dichloromethane → (1S,3R)-3-Ethoxycyclopentanamine

HRID 1548922Notes

Reaction equation

HRID 1548922 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][CH:10]([O:13][CH2:14][CH3:15])[CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:16].[Cl:24][CH2:25][Cl:26].[OH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23]>>[NH2:7][CH:8]1[CH2:9][CH:10]([O:13][CH2:14][CH3:15])[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 23568740tert-butyl N-(3-ethoxycyclopentyl)carbamate

Product 1

HCID 22170069(1S,3R)-3-Ethoxycyclopentanamine

Sources & evidence

ORD record
ord-5bf1bca623fa4394911c63148b81babd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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