Potassium Cation → 4-{[(2,4-Dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-2-(4-fluoro-phenyl)-thiazole-5-carboxylic acid ethyl ester

HRID 1549324Notes

Reaction equation

HRID 1549324 reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH2:18][Br:19])[n:8][c:9](-[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[s:10]1.[CH2:20]([CH3:21])[O:22][C:23]([CH2:24][NH:25][CH2:26][c:27]1[c:28]([O:35][CH3:36])[cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]1)=[O:37].[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[K+:42].[K+:43]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH2:18][N:25]([CH2:24][C:23]([O:22][CH2:20][CH3:21])=[O:37])[CH2:26][c:27]2[c:28]([O:35][CH3:36])[cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]2)[n:8][c:9](-[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[s:10]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 19895532Ethyl 2-(2,4-dimethoxybenzylamino)acetateHCID 684283654-Bromomethyl-2-(4-fluoro-phenyl)-thiazole-5-carboxylic acid ethyl ester

Product 1

HCID 684265514-{[(2,4-Dimethoxy-benzyl)-ethoxycarbonylmethyl-amino]-methyl}-2-(4-fluoro-phenyl)-thiazole-5-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-334137dcb94a45d59273fb4669211cab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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