1-Methylpiperazine → 6-Methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-4-one
Reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][O:5][c:6]1[c:7]([O:25][CH3:26])[cH:8][c:9]2[c:10](=[O:24])[n:11]([CH2:16][O:17][C:18]([C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[cH:12][n:13][c:14]2[cH:15]1.[CH3:27][N:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1>>[CH2:2]([CH2:3][CH2:4][O:5][c:6]1[c:7]([O:25][CH3:26])[cH:8][c:9]2[c:10](=[O:24])[n:11]([CH2:16][O:17][C:18]([C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[cH:12][n:13][c:14]2[cH:15]1)[N:31]1[CH2:30][CH2:29][N:28]([CH3:27])[CH2:33][CH2:32]1Participants
3
Sources & evidence
- ORD record
- ord-e557e49e74754e45ab73c8e25106137f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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