Isopropanol → 1-[trans-4-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl]-3-(4-methoxy-phenyl)-7-(3,4-dimethoxy-phenylamino)-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([N:13]2[C:14](=[O:32])[N:15]([c:24]3[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]3)[CH2:16][c:17]3[c:18]2[n:19][c:20]([Cl:23])[n:21][cH:22]3)[CH2:11][CH2:12]1)([CH3:33])[CH3:34].[CH3:46][CH:47]([OH:48])[CH3:49].[NH2:35][c:36]1[cH:37][c:38]([O:44][CH3:45])[c:39]([O:42][CH3:43])[cH:40][cH:41]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([N:13]2[C:14](=[O:32])[N:15]([c:24]3[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]3)[CH2:16][c:17]3[c:18]2[n:19][c:20]([NH:35][c:36]2[cH:37][c:38]([O:44][CH3:45])[c:39]([O:42][CH3:43])[cH:40][cH:41]2)[n:21][cH:22]3)[CH2:11][CH2:12]1)([CH3:33])[CH3:34]Participants
4
Sources & evidence
- ORD record
- ord-c3f3a6fe57674014b391f21200afd201
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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