Acetonitrile → 4-(2-Bromo-4-fluorobenzyl)morpholine

HRID 154982Notes

Reaction equation

HRID 154982 reaction equation
[Br:1][c:2]1[c:3]([CH2:9][Br:10])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[CH2:11]1[CH2:12][O:13][CH2:14][CH2:15][NH:16]1.[CH3:26][C:27]#[N:28].[CH:17]([N:18]([CH:19]([CH3:20])[CH3:21])[CH2:22][CH3:23])([CH3:24])[CH3:25]>>[Br:1][c:2]1[c:3]([CH2:9][N:16]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 8083MorpholineHCID 81531DiisopropylethylamineHCID 107069772-Bromo-1-(bromomethyl)-4-fluorobenzene

Product 1

HCID 510751744-(2-Bromo-4-fluorobenzyl)morpholine

Sources & evidence

ORD record
ord-76757915b70847cb96e829d8f39d1efb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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