Hydrochloric Acid → 2-(4'-(6-Carbamoyl-3,5-dimethylpyrazin-2-yl)-2,6-difluorobiphenyl-4-yl)acetic acid
Reaction equation
[C:3]([NH2:4])(=[O:5])[c:6]1[c:7]([CH3:32])[n:8][c:9]([CH3:31])[c:10](-[c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([F:30])[cH:20][c:21]([CH2:25][C:26](=[O:27])[O:28][CH3:29])[cH:22][c:23]3[F:24])[cH:16][cH:17]2)[n:11]1.[CH3:34][C:35]([OH:36])([CH3:37])[CH3:38].[ClH:33].[K+:2].[OH-:1]>>[C:3]([NH2:4])(=[O:5])[c:6]1[c:7]([CH3:32])[n:8][c:9]([CH3:31])[c:10](-[c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([F:30])[cH:20][c:21]([CH2:25][C:26](=[O:27])[OH:28])[cH:22][c:23]3[F:24])[cH:16][cH:17]2)[n:11]1Participants
6
Sources & evidence
- ORD record
- ord-738ce9be3da54b2891731d8d4cc34410
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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