Dimethylformamide → 10-{[2'-(Cyanomethyl)-1,1'-biphenyl-4-yl]carbonyl}-N-(pyridin-3-ylmethyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxamide
Reaction equation
[C:5](#[N:6])[CH2:7][c:8]1[c:9](-[c:14]2[cH:15][cH:16][c:17]([C:20](=[O:21])[OH:22])[cH:18][cH:19]2)[cH:10][cH:11][cH:12][cH:13]1.[CH2:52]1[O:53][CH2:54][CH2:55][O:56][CH2:57]1.[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[S:1]([Cl:2])([Cl:3])=[O:4].[n:23]1[cH:24][c:25]([CH2:29][NH:30][C:31](=[O:32])[c:33]2[cH:34][cH:35][c:36]3[n:42]2[CH2:41][c:40]2[c:39]([cH:46][cH:45][cH:44][cH:43]2)[NH:38][CH2:37]3)[cH:26][cH:27][cH:28]1>>[C:5](#[N:6])[CH2:7][c:8]1[c:9](-[c:14]2[cH:15][cH:16][c:17]([C:20](=[O:22])[N:38]3[CH2:37][c:36]4[cH:35][cH:34][c:33]([C:31]([NH:30][CH2:29][c:25]5[cH:24][n:23][cH:28][cH:27][cH:26]5)=[O:32])[n:42]4[CH2:41][c:40]4[c:39]3[cH:46][cH:45][cH:44][cH:43]4)[cH:18][cH:19]2)[cH:10][cH:11][cH:12][cH:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f5712af45b12432582f9185651662759
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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