Sodium ion → 3-Fluoro-4-{8-[4-(4-methylpiperazin-1-yl)phenylamino]imidazo[1,2-a]pyrazin-5-yl}benzamide
Reaction equation
[Br:20][c:21]1[cH:22][n:23][c:24]([NH:30][c:31]2[cH:32][cH:33][c:34]([N:37]3[CH2:38][CH2:39][N:40]([CH3:43])[CH2:41][CH2:42]3)[cH:35][cH:36]2)[c:25]2[n:26]1[cH:27][cH:28][n:29]2.[C:55](=[O:56])([O-:57])[O-:58].[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH2:7])[cH:8][cH:9][c:10]1[B:11]1[O:12][C:13]([CH3:14])([CH3:15])[C:16]([CH3:17])([CH3:18])[O:19]1.[Na+:59].[Na+:60].[O:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49]1.[O:50]=[CH:51][N:52]([CH3:53])[CH3:54].[cH:61]1[cH:62][cH:63][c:64]([P:65]([Pd:66]([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)([P:86]([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[P:105]([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)([c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)[c:118]2[cH:119][cH:120][cH:121][cH:122][cH:123]2)([c:124]2[cH:125][cH:126][cH:127][cH:128][cH:129]2)[c:130]2[cH:131][cH:132][cH:133][cH:134][cH:135]2)[cH:136][cH:137]1>>[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH2:7])[cH:8][cH:9][c:10]1-[c:21]1[cH:22][n:23][c:24]([NH:30][c:31]2[cH:32][cH:33][c:34]([N:37]3[CH2:38][CH2:39][N:40]([CH3:43])[CH2:41][CH2:42]3)[cH:35][cH:36]2)[c:25]2[n:26]1[cH:27][cH:28][n:29]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-803f85148eb3470386b38f065b1f22d5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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