Hydrogen Bromide → 3-[1-(2-Chloro-6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]-1-ethyl-1,2,3,4-tetrahydro-6-nitro-2,4-dioxoquinazoline
Reaction equation
[BrH:29].[CH2:1]([O:2][C:3](=[O:4])[N:6]1[CH2:7][CH2:8][CH:9]([n:12]2[c:13](=[O:28])[n:14]([CH2:26][CH3:27])[c:15]3[cH:16][cH:17][c:18]([N+:23](=[O:24])[O-:25])[cH:19][c:20]3[c:21]2=[O:22])[CH2:10][CH2:11]1)[CH3:5].[CH2:30]([n:31]1[c:32]2[c:33]([cH:34][c:35]([N+:36]([O-:37])=[O:38])[cH:39][cH:40]2)[c:41](=[O:42])[n:43]([CH:44]2[CH2:45][CH2:46][NH:47][CH2:48][CH2:49]2)[c:50]1=[O:51])[CH3:52].[Cl:53][c:54]1[n:55][c:56]2[cH:57][c:58]([O:67][CH3:68])[c:59]([O:65][CH3:66])[cH:60][c:61]2[c:62]([Cl:64])[n:63]1>>[N:6]1([c:62]2[c:61]3[c:56]([n:55][c:54]([Cl:53])[n:63]2)[cH:57][c:58]([O:67][CH3:68])[c:59]([O:65][CH3:66])[cH:60]3)[CH2:7][CH2:8][CH:9]([n:12]2[c:13](=[O:28])[n:14]([CH2:26][CH3:27])[c:15]3[cH:16][cH:17][c:18]([N+:23](=[O:24])[O-:25])[cH:19][c:20]3[c:21]2=[O:22])[CH2:10][CH2:11]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0e5618a8b4374244b6782ed01e5f5bd3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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