O-Xylene → 5-bromo-4-chloro-2-hydroxy-N-(2-methoxy-phenyl)-N-methyl-benzamide

HRID 1550447Notes

Reaction equation

HRID 1550447 reaction equation
[Br:1][c:2]1[c:3]([Cl:12])[cH:4][c:5]([OH:11])[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[CH3:13][O:14][c:15]1[c:16]([NH:17][CH3:18])[cH:19][cH:20][cH:21][cH:22]1.[O:23]=[P:24]12[O:25][P:26]3(=[O:36])[O:27][P:28](=[O:34])([O:29][P:30](=[O:33])([O:31]3)[O:32]1)[O:35]2.[c:37]1([CH3:38])[c:39]([CH3:40])[cH:41][cH:42][cH:43][cH:44]1>>[Br:1][c:2]1[c:3]([Cl:12])[cH:4][c:5]([OH:11])[c:6]([C:7](=[O:9])[N:17]([c:16]2[c:15]([O:14][CH3:13])[cH:22][cH:21][cH:20][cH:19]2)[CH3:18])[cH:10]1

Participants

5

Reactant 4

HCID 7237O-XyleneHCID 14812Phosphorus oxide (P4O10)HCID 27595792-Methoxy-N-methylanilineHCID 110213535-Bromo-4-chloro-2-hydroxybenzoic acid

Product 1

HCID 686025845-bromo-4-chloro-2-hydroxy-N-(2-methoxy-phenyl)-N-methyl-benzamide

Sources & evidence

ORD record
ord-780aa04463464baa971f0f3ad44a5a5f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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