1-Butanol → Tert-butyl 4-(1,1-dioxidothietan-3-yl)piperazine-1-carboxylate

HRID 1550636Notes

Reaction equation

HRID 1550636 reaction equation
[CH2:35]([OH:36])[CH2:37][CH2:38][CH3:39].[CH3:8][CH2:9][N:10]([CH2:11][CH3:12])[CH2:13][CH3:14].[Cl:1][CH:2]1[CH2:3][S:4](=[O:6])(=[O:7])[CH2:5]1.[NH2:15][c:16]1[n:17][cH:18][n:19][c:20]([N:22]2[CH2:23][CH2:24][N:25]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:26][CH2:27]2)[cH:21]1>>[CH:2]1([N:22]2[CH2:23][CH2:24][N:25]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:26][CH2:27]2)[CH2:3][S:4](=[O:6])(=[O:7])[CH2:5]1

Participants

5

Reactant 4

HCID 2631-ButanolHCID 8471TriethylamineHCID 2656363-Chloro-1lambda6-thietane-1,1-dioneHCID 21934614tert-Butyl 4-(6-aminopyrimidin-4-yl)piperazine-1-carboxylate

Product 1

HCID 21060000Tert-butyl 4-(1,1-dioxidothietan-3-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-9ed295f3a79f4d0ab7eba61c0b118d0f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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