Dichloromethane → 7-(4-Bromophenyl)-4-chloro-5,6-dihydropyrrolo[2,3-d]pyrimidine

HRID 1551121Notes

Reaction equation

HRID 1551121 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([NH2:6])[cH:7][cH:8]1.[Cl:27][CH2:28][Cl:29].[Cl:9][c:10]1[n:11][cH:12][n:13][c:14]([Cl:19])[c:15]1[CH2:16][CH:17]=[O:18].[F:20][C:21]([F:22])([F:23])[C:24]([OH:25])=[O:26]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:6]2[c:14]3[n:13][cH:12][n:11][c:10]([Cl:9])[c:15]3[CH2:16][CH2:17]2)[cH:7][cH:8]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 78074-BromoanilineHCID 13989292(4,6-Dichloropyrimidin-5-yl)acetaldehyde

Product 1

HCID 866374027-(4-Bromophenyl)-4-chloro-5,6-dihydropyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-9df847bdc533411db7070630cf0a308c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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